Prunus spinosa L. leaf extracts: polyphenol profile and bioactivities
نویسندگان
چکیده
Prunus spinosa leaf extracts in solvents of different polarity (water, ethanol and acetone), their phenol, flavonoid anthocyanin contents biological properties were the object this study. The richest phenols as well flavonoids was acetone extract with 181.19 mg GAE 80.10 QE per gram dry extract, respectively. Moreover, quantity anthocyanins obtained by HPLC analysis also highest sample. Examined samples possessed antioxidant evaluated through four vitro assays (DPPH, ABTS, FRAP TRC). proved to be best among tested samples, which could ascribed polyphenols, especially anthocyanins. aqueous exhibited antibacterial effects, being particularly active against B. cereus E. cloacae. T. viride, P. funiculosum, ochrochloron, verrucosum var. cyclopium most susceptible fungal microorganisms examined. Both, expressed inhibitory activity towards enzymes linked diabetes mellitus type II. Additionally, showed significantly higher potential inhibiting α-glucosidase than drug used positive control. Furthermore, sample revealed antitumor effects on following malignant cell lines: HeLa, K562 MDA-MB-453. results presented herein suggest that leaves should considered a natural source bioactive compounds application phytopharmacy food industry.
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ژورنال
عنوان ژورنال: Notulae Botanicae Horti Agrobotanici Cluj-napoca
سال: 2021
ISSN: ['0255-965X', '1842-4309']
DOI: https://doi.org/10.15835/nbha49112137